British anti-lewisite; arsenic and thiol excretion in animals after treatment of lewisite burns.
نویسندگان
چکیده
منابع مشابه
Clinical Uses of 2,3-dimercaptopropanol (bal). Vii. the Treatment of Arsenical Dermatitis with Preparations of Bal.
The development of 2,3-dimercaptopropanol (British Anti-Lewisite, BAL) by Peters, Stocken, and Thompson (1) has made available a potent antidote for arsenical poisoning. Study of the chemical combination of arsenic with sensitive enzymes and cells indicated that the arsenic could, under certain circumstances, be removed from the cells, and that enzymes could be reactivated by the action of BAL ...
متن کاملUse of BAL in the Treatment of Arsenical Neuropathy
BAL 01* British Anti-Lewisite which is 2, 3 dimercaptopropanol was evolved in Professor Peters' Laboratory at Oxford by Peters, Stocken and Thompson in 1945, as an effective antidote to Lewisite. It has since been used successfully in several forms of metallic poisoning including arsenic, mercury and other heavy metals. Eagle and Magnuson (1946) found it efficacious in 5 cases of arsenical ence...
متن کاملThe Dysenteric Disorders
gas is not destroyed but only dissolved, and care must be taken not to spread the contamination by allowing the solvent to run. lThorough washing with soap and water will complete the treatment. 3. T7horough washing with soap and water.-If some time has elapsed after contamination, the washing treatment should still be carried out at the first opportunity with the hopes of mitigating the degree...
متن کاملAcute arsenic poisoning: absence of polyneuropathy after treatment with 2,3-dimercaptopropanesulphonate (DMPS).
Two men aged 19 and 21 years ingested 1 g and 4 g respectively from 3 kg of a white crystalline powder that they thought was a substance of abuse. It was later identified as almost pure arsenic trioxide. Both had nausea and vomiting and one developed acute renal failure. Each was treated with 2,3-dimercaptopropanesulphonate (DMPS), and made a full recovery with no evidence of prolonged renal or...
متن کاملMobilization of heavy metals by newer, therapeutically useful chelating agents.
Four chelating agents that have been used most commonly for the treatment of humans intoxicated with lead, mercury, arsenic or other heavy metals and metalloids are reviewed as to their advantages, disadvantages, metabolism and specificity. Of these, CaNa2EDTA and dimercaprol (British anti-lewisite, BAL) are becoming outmoded and can be expected to be replaced by meso-2,3-dimercaptosuccinic aci...
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عنوان ژورنال:
- The Biochemical journal
دوره 40 4 شماره
صفحات -
تاریخ انتشار 1946